National Longevity Clinic London: Inside the New Harley Street Practice

At 69 Harley Street, a new National Longevity Clinic London is organising preventive care around more than a single test or speciality. The clinic opened in September 2026 and was founded by cardiologist Dr Francesco Lo Monaco and nutrition practitioner Audrey Elena Ottaviani-Lo Monaco.

National Longevity Clinic London: What the New Practice Offers

The clinic's model begins with a medical consultation, followed by assessment across what it describes as 11 interconnected body systems. Its published diagnostic programme includes 250+ biomarkers, genetic and gut-microbiome testing, biological-age assessment and VO₂ Max testing. The clinic also lists imaging and body-composition assessments among its diagnostic services.

The programme structure has also evolved into three longevity packages: ORIGIN, a weekend assessment; ASCEND, a month-long programme; and ZENITH, a three-month programme combining broader diagnostics with ongoing medical supervision and support. These descriptions reflect the clinic's own programme materials rather than evidence that the packages extend lifespan.

The Medical Team and Diagnostic Approach

The multidisciplinary team covers cardiology and cardiovascular prevention, women's health, men's health and urology, functional medicine, nutrition, mental health and clinical exercise.

For regulatory context, the National Heart Clinic Ltd, which operates clinical services at 69 Harley Street, is registered with the CQC for treatment and diagnostic and screening procedures. The CQC states that the Harley Street service has not yet been inspected or rated.

For anyone considering a longevity clinic London, the useful questions remain practical: who is medically responsible, which tests are clinically indicated, how abnormal findings are followed up, and which interventions have established evidence rather than emerging or limited evidence.